Role of channel activation in cognitive enhancement mediated by α7 nicotinic acetylcholine receptors

BACKGROUND AND PURPOSE: Several agonists of the α7 nicotinic acetylcholine receptor (nAChR) have been developed for treatment of cognitive deficits. However, agonist efficacy in vivo is difficult to reconcile with rapid α7 nAChR desensitization in vitro; and furthermore, the correlation between in v...

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Bibliografiska uppgifter
Huvudupphovsmän: Briggs, Clark A, Grønlien, Jens Halvard, Curzon, Peter, Timmermann, Daniel B, Ween, Hilde, Thorin-Hagene, Kirsten, Kerr, Paige, Anderson, David J, Malysz, John, Dyhring, Tino, Olsen, Gunnar M, Peters, Dan, Bunnelle, William H, Gopalakrishnan, Murali
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Publishing Ltd 2009
Ämnen:
Research Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795215/
https://ncbi.nlm.nih.gov/pubmed/19845675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00426.x
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