Distinct Brain Volume Changes Correlating with Clinical Stage, Disease Progression Rate, Mutation Size, and Age at Onset Prediction as Early Biomarkers of Brain Atrophy in Huntington's Disease

Searching brain and peripheral biomarkers is a requisite to cure Huntington's disease (HD). To search for markers indicating the rate of brain neurodegenerative changes in the various disease stages, we quantified changes in brain atrophy in subjects with HD. We analyzed the cross‐sectional and...

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Bibliographic Details
Published in:CNS Neurosci Ther
Main Authors: Squitieri, Ferdinando, Cannella, Milena, Simonelli, Maria, Sassone, Jenny, Martino, Tiziana, Venditti, Eugenio, Ciammola, Andrea, Colonnese, Claudio, Frati, Luigi, Ciarmiello, Andrea
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494025/
https://ncbi.nlm.nih.gov/pubmed/19228174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-5949.2008.00068.x
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