Distinct Brain Volume Changes Correlating with Clinical Stage, Disease Progression Rate, Mutation Size, and Age at Onset Prediction as Early Biomarkers of Brain Atrophy in Huntington's Disease

Searching brain and peripheral biomarkers is a requisite to cure Huntington's disease (HD). To search for markers indicating the rate of brain neurodegenerative changes in the various disease stages, we quantified changes in brain atrophy in subjects with HD. We analyzed the cross‐sectional and...

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Vydáno v:CNS Neurosci Ther
Hlavní autoři: Squitieri, Ferdinando, Cannella, Milena, Simonelli, Maria, Sassone, Jenny, Martino, Tiziana, Venditti, Eugenio, Ciammola, Andrea, Colonnese, Claudio, Frati, Luigi, Ciarmiello, Andrea
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2009
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494025/
https://ncbi.nlm.nih.gov/pubmed/19228174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-5949.2008.00068.x
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