Distinct Brain Volume Changes Correlating with Clinical Stage, Disease Progression Rate, Mutation Size, and Age at Onset Prediction as Early Biomarkers of Brain Atrophy in Huntington's Disease

Searching brain and peripheral biomarkers is a requisite to cure Huntington's disease (HD). To search for markers indicating the rate of brain neurodegenerative changes in the various disease stages, we quantified changes in brain atrophy in subjects with HD. We analyzed the cross‐sectional and...

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Detalhes bibliográficos
Publicado no:CNS Neurosci Ther
Main Authors: Squitieri, Ferdinando, Cannella, Milena, Simonelli, Maria, Sassone, Jenny, Martino, Tiziana, Venditti, Eugenio, Ciammola, Andrea, Colonnese, Claudio, Frati, Luigi, Ciarmiello, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494025/
https://ncbi.nlm.nih.gov/pubmed/19228174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-5949.2008.00068.x
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