Preclinical Characterization of A‐582941: A Novel α7 Neuronal Nicotinic Receptor Agonist with Broad Spectrum Cognition‐Enhancing Properties

Among the diverse sets of nicotinic acetylcholine receptors (nAChRs), the α7 subtype is highly expressed in the hippocampus and cortex and is thought to play important roles in a variety of cognitive processes. In this review, we describe the properties of a novel biaryl diamine α7 nAChR agonist, A‐...

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Detalhes bibliográficos
Publicado no:CNS Neurosci Ther
Main Authors: Tietje, Karin R., Anderson, David J., Bitner, R. Scott, Blomme, Eric A., Brackemeyer, Paul J., Briggs, Clark A., Browman, Kaitlin E., Bury, Dagmar, Curzon, Peter, Drescher, Karla U., Frost, Jennifer M., Fryer, Ryan M., Fox, Gerard B., Gronlien, Jens Halvard, Håkerud, Monika, Gubbins, Earl J., Halm, Sabine, Harris, Richard, Helfrich, Rosalind J., Kohlhaas, Kathy L., Law, Devalina, Malysz, John, Marsh, Kennan C., Martin, Ruth L., Meyer, Michael D., Molesky, Angela L., Nikkel, Arthur L., Otte, Stephani, Pan, Liping, Puttfarcken, Pamela S., Radek, Richard J., Robb, Holly M., Spies, Eva, Thorin‐Hagene, Kirsten, Waring, Jeffrey F., Ween, Hilde, Xu, Hongyu, Gopalakrishnan, Murali, Bunnelle, William H.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Inc 2008
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494002/
https://ncbi.nlm.nih.gov/pubmed/18482100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1527-3458.2008.00037.x
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