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Severe Arterial Hypertension from Cullin 3 Mutations Is Caused by Both Renal and Vascular Effects
BACKGROUND: Mutations in four genes, WNK lysine deficient protein kinase 1 and 4 (WNK1 and WNK4), kelch like family member 3 (KLHL3), or Cullin 3 (CUL3), can result in familial hyperkalemic hypertension (FHHt), a rare Mendelian form of human arterial hypertension. Although all mutations result in an...
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| Publicado no: | J Am Soc Nephrol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Nephrology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6493989/ https://ncbi.nlm.nih.gov/pubmed/30967423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017121307 |
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