Why Has the Antidepressant–Placebo Difference in Antidepressant Clinical Trials Diminished over the Past Three Decades?

The increasing rate of failure of antidepressant clinical trials has led to the assertion that antidepressants do not have meaningful clinical benefits. Our hypothesis was that the decrease in antidepressant–placebo differences in antidepressant clinical trials over the past three decades could be e...

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Bibliografiske detaljer
Udgivet i:CNS Neurosci Ther
Main Authors: Khan, Arif, Bhat, Amritha, Kolts, Russell, Thase, Michael E., Brown, Walter
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2010
Fag:
Depression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6493812/
https://ncbi.nlm.nih.gov/pubmed/20406269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-5949.2010.00151.x
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