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Why Has the Antidepressant–Placebo Difference in Antidepressant Clinical Trials Diminished over the Past Three Decades?

The increasing rate of failure of antidepressant clinical trials has led to the assertion that antidepressants do not have meaningful clinical benefits. Our hypothesis was that the decrease in antidepressant–placebo differences in antidepressant clinical trials over the past three decades could be e...

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Detalhes bibliográficos
Publicado no:CNS Neurosci Ther
Main Authors: Khan, Arif, Bhat, Amritha, Kolts, Russell, Thase, Michael E., Brown, Walter
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6493812/
https://ncbi.nlm.nih.gov/pubmed/20406269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-5949.2010.00151.x
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