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Combining multiple structure and sequence alignments to improve sequence detection and alignment: Application to the SH2 domains of Janus kinases

In this paper, an approach is described that combines multiple structure alignments and multiple sequence alignments to generate sequence profiles for protein families. First, multiple sequence alignments are generated from sequences that are closely related to each sequence of known three-dimension...

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Autors principals: Al-Lazikani, Bissan, Sheinerman, Felix B., Honig, Barry
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC64938/
https://ncbi.nlm.nih.gov/pubmed/11752426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.011577898
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