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Combining multiple structure and sequence alignments to improve sequence detection and alignment: Application to the SH2 domains of Janus kinases

In this paper, an approach is described that combines multiple structure alignments and multiple sequence alignments to generate sequence profiles for protein families. First, multiple sequence alignments are generated from sequences that are closely related to each sequence of known three-dimension...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Al-Lazikani, Bissan, Sheinerman, Felix B., Honig, Barry
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2001
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC64938/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11752426/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.011577898
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