The Transcription Factor ERG Regulates Super-Enhancers Associated With an Endothelial-Specific Gene Expression Program

RATIONALE: The ETS (E-26 transformation-specific) transcription factor ERG (ETS-related gene) is essential for endothelial homeostasis, driving expression of lineage genes and repressing proinflammatory genes. Loss of ERG expression is associated with diseases including atherosclerosis. ERG’s homeos...

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Dettagli Bibliografici
Pubblicato in:Circ Res
Autori principali: Kalna, Viktoria, Yang, Youwen, Peghaire, Claire R., Frudd, Karen, Hannah, Rebecca, Shah, Aarti V., Osuna Almagro, Lourdes, Boyle, Joseph J., Göttgens, Berthold, Ferrer, Jorge, Randi, Anna M., Birdsey, Graeme M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2019
Soggetti:
Cellular Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6493686/
https://ncbi.nlm.nih.gov/pubmed/30892142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.118.313788
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