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Aquaporin‐4 Deficiency Attenuates Opioid Dependence through Suppressing Glutamate Transporter‐1 Down‐regulation and Maintaining Glutamate Homeostasis

BACKGROUND: Glutamate homeostasis plays a critical role in mediating the addiction‐related behaviors. Therefore, preventing the disruption or reestablishing of it is a novel strategy for the treatment of addiction. Glutamate transporters are responsible for clearing extracellular glutamate and maint...

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Опубликовано в: :CNS Neurosci Ther
Главные авторы: Yan, Hai‐Tao, Wu, Ning, Lu, Xin‐Qiang, Su, Rui‐Bin, Zheng, Jian‐Quan, Li, Jin
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6493630/
https://ncbi.nlm.nih.gov/pubmed/23051665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12012
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