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T regulatory cells maintain intestinal homeostasis by suppressing γδ T cells

Immune tolerance against enteric commensal bacteria is important for preventing intestinal inflammation. Deletion of phosphoinositide dependent protein kinase 1 (Pdk1) in T cells using Cd4-Cre induced chronic inflammation of the intestine despite the importance of PDK1 in T cell activation. Analysis...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Park, Sung-Gyoo, Mathur, Ramkumar, Long, Meixiao, Hosh, Namiko, Hao, Liming, Hayden, Matthew S., Ghosh, Sankar
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996054/
https://ncbi.nlm.nih.gov/pubmed/21074460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.10.014
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