Evaluation of gilteritinib in combination with chemotherapy in preclinical models of FLT3-ITD(+) acute myeloid leukemia

Activating internal tandem duplication (ITD) and tyrosine kinase domain (TKD) point mutations in Fms-like tyrosine kinase 3 (FLT3) occur in approximately 30% of patients with acute myeloid leukemia (AML), and confer a poor prognosis with standard cytarabine/anthracycline or azacitidine-based chemoth...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncotarget
Päätekijät: Ueno, Yoko, Mori, Masamichi, Kamiyama, Yoshiteru, Saito, Rika, Kaneko, Naoki, Isshiki, Eriko, Kuromitsu, Sadao, Takeuchi, Masahiro
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2019
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6493465/
https://ncbi.nlm.nih.gov/pubmed/31069015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26811
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia