Substantial Neuroprotection Against K (+) Deprivation‐Induced Apoptosis in Primary Cerebellar Granule Neurons by Novel Dimer Bis(propyl)‐Cognitin Via the Activation of VEGFR‐2 Signaling Pathway

BACKGROUND: Neuronal loss via apoptosis in CNS is the fundamental mechanism underlying various neurodegenerative diseases. Compounds with antiapoptotic property might have therapeutic effects for these diseases. In this study, bis(propyl)‐cognitin (B3C), a novel dimer that possesses anti‐AChE and an...

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Detalhes bibliográficos
Publicado no:CNS Neurosci Ther
Main Authors: Hu, Sheng‐Quan, Cui, Wei, Xu, Da‐Ping, Mak, Shing‐Hung, Tang, Jing, Choi, Chung‐Lit, Pang, Yuan‐Ping, Han, Yi‐Fan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2013
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6493391/
https://ncbi.nlm.nih.gov/pubmed/23826635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12141
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