Dimeric bis (heptyl)‐Cognitin Blocks Alzheimer's β‐Amyloid Neurotoxicity Via the Inhibition of Aβ Fibrils Formation and Disaggregation of Preformed Fibrils

AIMS: Fibrillar aggregates of β‐amyloid protein (Aβ) are the main constituent of senile plaques and considered to be one of the causative events in the pathogenesis of Alzheimer's disease (AD). Compounds that could inhibit Aβ fibrils formation, disaggregate preformed Aβ fibrils as well as reduc...

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Detalhes bibliográficos
Publicado no:CNS Neurosci Ther
Main Authors: Hu, Sheng‐Quan, Wang, Rui, Cui, Wei, Mak, Shing‐Hung, Li, Gang, Hu, Yuan‐Jia, Lee, Ming‐Yuen, Pang, Yuan‐Ping, Han, Yi‐Fan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6493105/
https://ncbi.nlm.nih.gov/pubmed/26507365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12472
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