Dimeric bis (heptyl)‐Cognitin Blocks Alzheimer's β‐Amyloid Neurotoxicity Via the Inhibition of Aβ Fibrils Formation and Disaggregation of Preformed Fibrils

AIMS: Fibrillar aggregates of β‐amyloid protein (Aβ) are the main constituent of senile plaques and considered to be one of the causative events in the pathogenesis of Alzheimer's disease (AD). Compounds that could inhibit Aβ fibrils formation, disaggregate preformed Aβ fibrils as well as reduc...

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Publicat a:CNS Neurosci Ther
Autors principals: Hu, Sheng‐Quan, Wang, Rui, Cui, Wei, Mak, Shing‐Hung, Li, Gang, Hu, Yuan‐Jia, Lee, Ming‐Yuen, Pang, Yuan‐Ping, Han, Yi‐Fan
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2015
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6493105/
https://ncbi.nlm.nih.gov/pubmed/26507365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12472
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