Astrocytic JWA Expression is Essential to Dopaminergic Neuron Survival in the Pathogenesis of Parkinson's Disease

AIMS: To investigate the role of astrocytic JWA expression in dopaminergic (DA) neuron degeneration and in the pathogenesis of Parkinson's disease (PD). METHODS: Conditional astrocytic JWA null (JWA (∆2/∆2)/GFAP‐Cre) mice and U251 glioma cells were used to evaluate the effects of JWA gene on DA...

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Bibliographic Details
Published in:CNS Neurosci Ther
Main Authors: Miao, Shu‐Han, Sun, Hong‐Bin, Ye, Yang, Yang, Jing‐Jing, Shi, Yao‐Wei, Lu, Ming, Hu, Gang, Zhou, Jian‐Wei
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2014
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6493088/
https://ncbi.nlm.nih.gov/pubmed/24628733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12249
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