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Astrocytic JWA deletion exacerbates dopaminergic neurodegeneration by decreasing glutamate transporters in mice

Astrocytic JWA exerts neuroprotective roles by alleviating oxidative stress and inhibiting inflammation. However, the molecular mechanisms of how astrocytic JWA is involved in dopaminergic neurodegeneration in Parkinson’s disease (PD) remain largely unknown. In this study, we found that astrocyte-sp...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wang, Rihua, Zhao, Xue, Xu, Jin, Wen, Yifan, Li, Aiping, Lu, Ming, Zhou, Jianwei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834463/
https://ncbi.nlm.nih.gov/pubmed/29500411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0381-8
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