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Noradrenergic Terminals Regulate l‐DOPA‐derived Dopamine Extracellular Levels in a Region‐dependent Manner in Parkinsonian Rats

AIMS: Serotonin (5‐HT) neurons mediate the ectopic release of dopamine (DA) induced by l‐DOPA in the Parkinsonian brain. We hypothesized that the participation of noradrenalin transporters (NET) in the clearance of DA may account for the lower effect of l‐DOPA in extrastriatal regions compared with...

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Bibliografski detalji
Izdano u:CNS Neurosci Ther
Glavni autori: Navailles, Sylvia, Milan, Léa, Khalki, Hanane, Di Giovanni, Giuseppe, Lagière, Mélanie, De Deurwaerdère, Philippe
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6493006/
https://ncbi.nlm.nih.gov/pubmed/24775184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12275
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