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Noradrenergic Terminals Regulate l‐DOPA‐derived Dopamine Extracellular Levels in a Region‐dependent Manner in Parkinsonian Rats

AIMS: Serotonin (5‐HT) neurons mediate the ectopic release of dopamine (DA) induced by l‐DOPA in the Parkinsonian brain. We hypothesized that the participation of noradrenalin transporters (NET) in the clearance of DA may account for the lower effect of l‐DOPA in extrastriatal regions compared with...

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Bibliografiske detaljer
Udgivet i:CNS Neurosci Ther
Main Authors: Navailles, Sylvia, Milan, Léa, Khalki, Hanane, Di Giovanni, Giuseppe, Lagière, Mélanie, De Deurwaerdère, Philippe
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6493006/
https://ncbi.nlm.nih.gov/pubmed/24775184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12275
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