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Noradrenergic Terminals Regulate l‐DOPA‐derived Dopamine Extracellular Levels in a Region‐dependent Manner in Parkinsonian Rats

AIMS: Serotonin (5‐HT) neurons mediate the ectopic release of dopamine (DA) induced by l‐DOPA in the Parkinsonian brain. We hypothesized that the participation of noradrenalin transporters (NET) in the clearance of DA may account for the lower effect of l‐DOPA in extrastriatal regions compared with...

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Bibliografische gegevens
Gepubliceerd in:CNS Neurosci Ther
Hoofdauteurs: Navailles, Sylvia, Milan, Léa, Khalki, Hanane, Di Giovanni, Giuseppe, Lagière, Mélanie, De Deurwaerdère, Philippe
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6493006/
https://ncbi.nlm.nih.gov/pubmed/24775184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12275
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