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Multiple Mechanisms Underlying the Long Duration of Action of Thienorphine, A Novel Partial Opioid Agonist for the Treatment of Addiction

AIMS: It is considered that a long‐acting therapy would be advantageous in the treatment of addiction. In a search for novel buprenorphine analogues, thienorphine was demonstrated to be an extremely long‐acting orally active partial opioid agonist. This study explored the mechanisms underlying the l...

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Publicat a:CNS Neurosci Ther
Autors principals: Yu, Gang, Li, Shu‐Hui, Cui, Meng‐Xun, Yan, Ling‐Di, Yong, Zheng, Zhou, Pei‐Lan, Su, Rui‐Bin, Gong, Ze‐Hui
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492997/
https://ncbi.nlm.nih.gov/pubmed/24330593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12210
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