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Gem Depletion: Amyotrophic Lateral Sclerosis and Spinal Muscular Atrophy Crossover
The determining factor of spinal muscular atrophy (SMA), the most common motor neuron degenerative disease of childhood, is the survival motor neuron (SMN) protein. SMN and its Gemin associates form a complex that is indispensible for the biogenesis of small nuclear ribonucleoproteins (snRNPs), whic...
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| Publicado en: | CNS Neurosci Ther |
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| Autor Principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6492989/ https://ncbi.nlm.nih.gov/pubmed/24645792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12242 |
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