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TDP-43 expression in mouse models of amyotrophic lateral sclerosis and spinal muscular atrophy
BACKGROUND: Redistribution of nuclear TAR DNA binding protein 43 (TDP-43) to the cytoplasm and ubiquitinated inclusions of spinal motor neurons and glial cells is characteristic of amyotrophic lateral sclerosis (ALS) pathology. Recent evidence suggests that TDP-43 pathology is common to sporadic ALS...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2583980/ https://ncbi.nlm.nih.gov/pubmed/18957104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-9-104 |
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