A replication-incompetent CD154/40L recombinant vaccinia virus induces direct and macrophage-mediated antitumor effects in vitro and in vivo

CD40 triggering may result in antitumor effects of potentially high clinical relevance. To gain insights important for patient selection and to identify adequate targeting techniques, we investigated CD40 expression in human cancer tissues and generated a replication-incompetent recombinant vaccinia...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Governa, Valeria, Brittoli, Alvaro, Mele, Valentina, Pinamonti, Maurizio, Terracciano, Luigi, Muenst, Simone, Iezzi, Giandomenica, Spagnoli, Giulio Cesare, Zajac, Paul, Trella, Emanuele
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492963/
https://ncbi.nlm.nih.gov/pubmed/31069131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1568162
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