A replication-incompetent CD154/40L recombinant vaccinia virus induces direct and macrophage-mediated antitumor effects in vitro and in vivo

CD40 triggering may result in antitumor effects of potentially high clinical relevance. To gain insights important for patient selection and to identify adequate targeting techniques, we investigated CD40 expression in human cancer tissues and generated a replication-incompetent recombinant vaccinia...

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Publicat a:Oncoimmunology
Autors principals: Governa, Valeria, Brittoli, Alvaro, Mele, Valentina, Pinamonti, Maurizio, Terracciano, Luigi, Muenst, Simone, Iezzi, Giandomenica, Spagnoli, Giulio Cesare, Zajac, Paul, Trella, Emanuele
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2019
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492963/
https://ncbi.nlm.nih.gov/pubmed/31069131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1568162
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