A replication-incompetent CD154/40L recombinant vaccinia virus induces direct and macrophage-mediated antitumor effects in vitro and in vivo

CD40 triggering may result in antitumor effects of potentially high clinical relevance. To gain insights important for patient selection and to identify adequate targeting techniques, we investigated CD40 expression in human cancer tissues and generated a replication-incompetent recombinant vaccinia...

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Vydáno v:Oncoimmunology
Hlavní autoři: Governa, Valeria, Brittoli, Alvaro, Mele, Valentina, Pinamonti, Maurizio, Terracciano, Luigi, Muenst, Simone, Iezzi, Giandomenica, Spagnoli, Giulio Cesare, Zajac, Paul, Trella, Emanuele
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2019
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492963/
https://ncbi.nlm.nih.gov/pubmed/31069131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1568162
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