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Morphological and Functional Attenuation of Degeneration of Peripheral Neurons by Mesenchymal Stem Cell‐Conditioned Medium in Spinocerebellar Ataxia Type 1‐Knock‐in Mice

AIMS: Spinocerebellar ataxia type 1 (SCA1) is caused by the ataxin‐1 protein (ATXN1) with an abnormally expanded polyglutamine tract and is characterized by progressive neurodegeneration. We previously showed that intrathecal injection of mesenchymal stem cells (MSCs) during the nonsymptomatic stage...

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Detalhes bibliográficos
Publicado no:CNS Neurosci Ther
Main Authors: Suto, Nana, Mieda, Tokue, Iizuka, Akira, Nakamura, Kazuhiro, Hirai, Hirokazu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492824/
https://ncbi.nlm.nih.gov/pubmed/27140210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12560
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