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Inhibiting the Migration of M1 Microglia at Hyperacute Period Could Improve Outcome of tMCAO Rats

AIM: To study whether inhibiting microglia migration to the ischemic boundary zone (IBZ) at the early phase could improve neurological outcomes after stroke. METHODS: The transient middle cerebral artery occlusion (tMCAO) was induced in adult male Sprague‐Dawley rats. AMD3100, a highly selective CXC...

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Publicat a:CNS Neurosci Ther
Autors principals: Huang, Ming, Wan, Yan, Mao, Ling, He, Quan‐Wei, Xia, Yuan‐Peng, Li, Man, Li, Ya‐Nan, Jin, Hui‐Juan, Hu, Bo
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492671/
https://ncbi.nlm.nih.gov/pubmed/27991729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12665
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