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Potentiation of spinal glutamatergic response in the neuron‐glia interactions underlies the intrathecal IL‐1β‐induced thermal hyperalgesia in rats

AIMS: We previously demonstrated that intrathecal IL‐1β upregulated phosphorylation of p38 mitogen‐activated protein kinase (P‐p38 MAPK) and inducible nitric oxide synthase (iNOS) in microglia and astrocytes in spinal cord, increased nitric oxide (NO) release into cerebrospinal fluid, and induced th...

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Detalhes bibliográficos
Publicado no:CNS Neurosci Ther
Main Authors: Sung, Chun‐Sung, Wen, Zhi‐Hong, Feng, Chien‐Wei, Chen, Chun‐Hong, Huang, Shi‐Ying, Chen, Nan‐Fu, Chen, Wu‐Fu, Wong, Chih‐Shung
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492640/
https://ncbi.nlm.nih.gov/pubmed/28544775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12705
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