Potentiation of spinal glutamatergic response in the neuron‐glia interactions underlies the intrathecal IL‐1β‐induced thermal hyperalgesia in rats

AIMS: We previously demonstrated that intrathecal IL‐1β upregulated phosphorylation of p38 mitogen‐activated protein kinase (P‐p38 MAPK) and inducible nitric oxide synthase (iNOS) in microglia and astrocytes in spinal cord, increased nitric oxide (NO) release into cerebrospinal fluid, and induced th...

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Dettagli Bibliografici
Pubblicato in:CNS Neurosci Ther
Autori principali: Sung, Chun‐Sung, Wen, Zhi‐Hong, Feng, Chien‐Wei, Chen, Chun‐Hong, Huang, Shi‐Ying, Chen, Nan‐Fu, Chen, Wu‐Fu, Wong, Chih‐Shung
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492640/
https://ncbi.nlm.nih.gov/pubmed/28544775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12705
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