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Intracisternal or intrathecal glycine, taurine, or muscimol inhibit bicuculline-induced allodynia and thermal hyperalgesia in mice

AIM: To investigate the effects of GABA and glycine on analgesia in the central nervous system. METHODS: Glycine, taurine, or muscimol was injected with bicuculline into the cistern magna or the lumbar subarachnoidal space in ICR mice. The effects on bicuculline-induced allodynia in a touch-evoked a...

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Autores principales: Lee, Il-ok, Lim, Eui-sung
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007821/
https://ncbi.nlm.nih.gov/pubmed/20686515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.82
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