Potentiation of spinal glutamatergic response in the neuron‐glia interactions underlies the intrathecal IL‐1β‐induced thermal hyperalgesia in rats

AIMS: We previously demonstrated that intrathecal IL‐1β upregulated phosphorylation of p38 mitogen‐activated protein kinase (P‐p38 MAPK) and inducible nitric oxide synthase (iNOS) in microglia and astrocytes in spinal cord, increased nitric oxide (NO) release into cerebrospinal fluid, and induced th...

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Vydáno v:CNS Neurosci Ther
Hlavní autoři: Sung, Chun‐Sung, Wen, Zhi‐Hong, Feng, Chien‐Wei, Chen, Chun‐Hong, Huang, Shi‐Ying, Chen, Nan‐Fu, Chen, Wu‐Fu, Wong, Chih‐Shung
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492640/
https://ncbi.nlm.nih.gov/pubmed/28544775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12705
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