Impaired CpG Demethylation in Common Variable Immunodeficiency Associates With B Cell Phenotype and Proliferation Rate

Common Variable Immunodeficiency (CVID) is characterized by impaired antibody production and poor terminal differentiation of the B cell compartment, yet its pathogenesis is still poorly understood. We first reported the occurrence of epigenetic alterations in CVID by high-throughput methylation ana...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Immunol
Egile Nagusiak: del Pino-Molina, Lucía, Rodríguez-Ubreva, Javier, Torres Canizales, Juan, Coronel-Díaz, María, Kulis, Marta, Martín-Subero, José I., van der Burg, Mirjam, Ballestar, Esteban, López-Granados, Eduardo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2019
Gaiak:
Immunology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492528/
https://ncbi.nlm.nih.gov/pubmed/31105700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00878
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