Emergence of the Dedifferentiated Phenotype in Hepatocyte‐Derived Tumors in Mice: Roles of Oncogene‐Induced Epigenetic Alterations

Hepatocellular carcinoma often reactivates the genes that are transiently expressed in fetal or neonatal livers. However, the mechanism of their activation has not been elucidated. To explore how oncogenic signaling pathways could be involved in the process, we examined the expression of fetal/neona...

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Опубликовано в: :Hepatol Commun
Главные авторы: Watanabe, Kenji, Yamamoto, Masahiro, Xin, Bing, Ooshio, Takako, Goto, Masanori, Fujii, Kiyonaga, Liu, Yang, Okada, Yoko, Furukawa, Hiroyuki, Nishikawa, Yuji
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2019
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Original Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492474/
https://ncbi.nlm.nih.gov/pubmed/31061957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1327
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