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Emergence of the Dedifferentiated Phenotype in Hepatocyte‐Derived Tumors in Mice: Roles of Oncogene‐Induced Epigenetic Alterations

Hepatocellular carcinoma often reactivates the genes that are transiently expressed in fetal or neonatal livers. However, the mechanism of their activation has not been elucidated. To explore how oncogenic signaling pathways could be involved in the process, we examined the expression of fetal/neona...

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Detalhes bibliográficos
Publicado no:Hepatol Commun
Main Authors: Watanabe, Kenji, Yamamoto, Masahiro, Xin, Bing, Ooshio, Takako, Goto, Masanori, Fujii, Kiyonaga, Liu, Yang, Okada, Yoko, Furukawa, Hiroyuki, Nishikawa, Yuji
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492474/
https://ncbi.nlm.nih.gov/pubmed/31061957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1327
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