Inter‐ and intra‐tumoural heterogeneity in cancer‐associated fibroblasts of human pancreatic ductal adenocarcinoma

Cancer‐associated fibroblasts (CAF) are orchestrators of the pancreatic ductal adenocarcinoma (PDAC) microenvironment. Stromal heterogeneity may explain differential pathophysiological roles of the stroma (pro‐ versus anti‐tumoural) in PDAC. We hypothesised that multiple CAF functional subtypes exis...

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Vydáno v:J Pathol
Hlavní autoři: Neuzillet, Cindy, Tijeras‐Raballand, Annemilaï, Ragulan, Chanthirika, Cros, Jérôme, Patil, Yatish, Martinet, Matthieu, Erkan, Mert, Kleeff, Jörg, Wilson, Jeremy, Apte, Minoti, Tosolini, Marie, Wilson, Abigail S, Delvecchio, Francesca R, Bousquet, Corinne, Paradis, Valérie, Hammel, Pascal, Sadanandam, Anguraj, Kocher, Hemant M
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Ltd 2019
Témata:
Original Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492001/
https://ncbi.nlm.nih.gov/pubmed/30575030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5224
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