Inter‐ and intra‐tumoural heterogeneity in cancer‐associated fibroblasts of human pancreatic ductal adenocarcinoma

Cancer‐associated fibroblasts (CAF) are orchestrators of the pancreatic ductal adenocarcinoma (PDAC) microenvironment. Stromal heterogeneity may explain differential pathophysiological roles of the stroma (pro‐ versus anti‐tumoural) in PDAC. We hypothesised that multiple CAF functional subtypes exis...

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Udgivet i:J Pathol
Main Authors: Neuzillet, Cindy, Tijeras‐Raballand, Annemilaï, Ragulan, Chanthirika, Cros, Jérôme, Patil, Yatish, Martinet, Matthieu, Erkan, Mert, Kleeff, Jörg, Wilson, Jeremy, Apte, Minoti, Tosolini, Marie, Wilson, Abigail S, Delvecchio, Francesca R, Bousquet, Corinne, Paradis, Valérie, Hammel, Pascal, Sadanandam, Anguraj, Kocher, Hemant M
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2019
Fag:
Original Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492001/
https://ncbi.nlm.nih.gov/pubmed/30575030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5224
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