Inter‐ and intra‐tumoural heterogeneity in cancer‐associated fibroblasts of human pancreatic ductal adenocarcinoma

Cancer‐associated fibroblasts (CAF) are orchestrators of the pancreatic ductal adenocarcinoma (PDAC) microenvironment. Stromal heterogeneity may explain differential pathophysiological roles of the stroma (pro‐ versus anti‐tumoural) in PDAC. We hypothesised that multiple CAF functional subtypes exis...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Neuzillet, Cindy, Tijeras‐Raballand, Annemilaï, Ragulan, Chanthirika, Cros, Jérôme, Patil, Yatish, Martinet, Matthieu, Erkan, Mert, Kleeff, Jörg, Wilson, Jeremy, Apte, Minoti, Tosolini, Marie, Wilson, Abigail S, Delvecchio, Francesca R, Bousquet, Corinne, Paradis, Valérie, Hammel, Pascal, Sadanandam, Anguraj, Kocher, Hemant M
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2019
Assuntos:
Original Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492001/
https://ncbi.nlm.nih.gov/pubmed/30575030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5224
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