Priming of HIV-1-specific CD8(+) T cells with strong functional properties from naïve T cells

BACKGROUND: HIV-1-specific CD8(+) T cells are required for immune suppression of HIV-1 replication and elimination of the associated viral reservoirs. However, effective induction of functional HIV-1-specific CD8(+) T cells from naïve cells remains problematic in the setting of human vaccine trials....

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Kuse, Nozomi, Sun, Xiaoming, Akahoshi, Tomohiro, Lissina, Anna, Yamamoto, Takuya, Appay, Victor, Takiguchi, Masafumi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491959/
https://ncbi.nlm.nih.gov/pubmed/30956171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.03.078
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