The STING ligand cGAMP potentiates the efficacy of vaccine-induced CD8(+) T cells

Pathogen recognition receptor (PRR) agonists are currently being developed and tested as adjuvants in various formulations to optimize the immunogenicity and efficacy of vaccines. Using an original in vitro approach to prime naive precursors from unfractionated human peripheral blood mononuclear cel...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Gutjahr, Alice, Papagno, Laura, Nicoli, Francesco, Kanuma, Tomohiro, Kuse, Nozomi, Cabral-Piccin, Mariela Pires, Rochereau, Nicolas, Gostick, Emma, Lioux, Thierry, Perouzel, Eric, Price, David A., Takiguchi, Masafumi, Verrier, Bernard, Yamamoto, Takuya, Paul, Stéphane, Appay, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483644/
https://ncbi.nlm.nih.gov/pubmed/30944257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.125107
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