The STING ligand cGAMP potentiates the efficacy of vaccine-induced CD8(+) T cells

Pathogen recognition receptor (PRR) agonists are currently being developed and tested as adjuvants in various formulations to optimize the immunogenicity and efficacy of vaccines. Using an original in vitro approach to prime naive precursors from unfractionated human peripheral blood mononuclear cel...

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Vydáno v:JCI Insight
Hlavní autoři: Gutjahr, Alice, Papagno, Laura, Nicoli, Francesco, Kanuma, Tomohiro, Kuse, Nozomi, Cabral-Piccin, Mariela Pires, Rochereau, Nicolas, Gostick, Emma, Lioux, Thierry, Perouzel, Eric, Price, David A., Takiguchi, Masafumi, Verrier, Bernard, Yamamoto, Takuya, Paul, Stéphane, Appay, Victor
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483644/
https://ncbi.nlm.nih.gov/pubmed/30944257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.125107
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