The Mechanical Stimulation of Myotubes Counteracts the Effects of Tumor-Derived Factors Through the Modulation of the Activin/Follistatin Ratio

Activin negatively affects muscle fibers and progenitor cells in aging (sarcopenia) and in chronic diseases characterized by severe muscle wasting (cachexia). High circulating activin levels predict poor survival in cancer patients. However, the relative impact of activin in mediating muscle atrophy...

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Publicat a:Front Physiol
Autors principals: Baccam, Alexandra, Benoni-Sviercovich, Alexandra, Rocchi, Marco, Moresi, Viviana, Seelaender, Marilia, Li, Zhenlin, Adamo, Sergio, Xue, Zhigang, Coletti, Dario
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491697/
https://ncbi.nlm.nih.gov/pubmed/31068826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00401
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