The Mechanical Stimulation of Myotubes Counteracts the Effects of Tumor-Derived Factors Through the Modulation of the Activin/Follistatin Ratio

Activin negatively affects muscle fibers and progenitor cells in aging (sarcopenia) and in chronic diseases characterized by severe muscle wasting (cachexia). High circulating activin levels predict poor survival in cancer patients. However, the relative impact of activin in mediating muscle atrophy...

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Bibliografische gegevens
Gepubliceerd in:Front Physiol
Hoofdauteurs: Baccam, Alexandra, Benoni-Sviercovich, Alexandra, Rocchi, Marco, Moresi, Viviana, Seelaender, Marilia, Li, Zhenlin, Adamo, Sergio, Xue, Zhigang, Coletti, Dario
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2019
Onderwerpen:
Physiology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491697/
https://ncbi.nlm.nih.gov/pubmed/31068826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00401
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