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The Mechanical Stimulation of Myotubes Counteracts the Effects of Tumor-Derived Factors Through the Modulation of the Activin/Follistatin Ratio

Activin negatively affects muscle fibers and progenitor cells in aging (sarcopenia) and in chronic diseases characterized by severe muscle wasting (cachexia). High circulating activin levels predict poor survival in cancer patients. However, the relative impact of activin in mediating muscle atrophy...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Baccam, Alexandra, Benoni-Sviercovich, Alexandra, Rocchi, Marco, Moresi, Viviana, Seelaender, Marilia, Li, Zhenlin, Adamo, Sergio, Xue, Zhigang, Coletti, Dario
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491697/
https://ncbi.nlm.nih.gov/pubmed/31068826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00401
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