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Evaluating and Correcting Inherent Bias of microRNA Expression in Illumina Sequencing Analysis

microRNA (miRNA) expression profiles based on the highly powerful Illumina sequencing technology rely on the construction of cDNA libraries in which adaptor ligation is known to deeply favor some miRNAs over others. This introduces erroneous measurements of the miRNA abundances and relative miRNA qu...

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Bibliografski detalji
Izdano u:Front Mol Biosci
Glavni autori: Baroin-Tourancheau, Anne, Jaszczyszyn, Yan, Benigni, Xavier, Amar, Laurence
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491513/
https://ncbi.nlm.nih.gov/pubmed/31069233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2019.00017
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