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Evaluating and Correcting Inherent Bias of microRNA Expression in Illumina Sequencing Analysis

microRNA (miRNA) expression profiles based on the highly powerful Illumina sequencing technology rely on the construction of cDNA libraries in which adaptor ligation is known to deeply favor some miRNAs over others. This introduces erroneous measurements of the miRNA abundances and relative miRNA qu...

詳細記述

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書誌詳細
出版年:Front Mol Biosci
主要な著者: Baroin-Tourancheau, Anne, Jaszczyszyn, Yan, Benigni, Xavier, Amar, Laurence
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491513/
https://ncbi.nlm.nih.gov/pubmed/31069233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2019.00017
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