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Propagation and Selectivity of Axonal Loss in Leber Hereditary Optic Neuropathy
Leber hereditary optic neuropathy (LHON) is a syndrome of subacute loss of central vision associated with mutations in mitochondrial DNA coding for components of complex I. LHON preferentially involves small axons in the temporal optic nerve, but the reason is unclear. We performed a Monte Carlo sim...
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| Опубликовано в: : | Sci Rep |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6491426/ https://ncbi.nlm.nih.gov/pubmed/31040363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43180-z |
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