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Propagation and Selectivity of Axonal Loss in Leber Hereditary Optic Neuropathy

Leber hereditary optic neuropathy (LHON) is a syndrome of subacute loss of central vision associated with mutations in mitochondrial DNA coding for components of complex I. LHON preferentially involves small axons in the temporal optic nerve, but the reason is unclear. We performed a Monte Carlo sim...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Coussa, Razek Georges, Merat, Pooya, Levin, Leonard A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491426/
https://ncbi.nlm.nih.gov/pubmed/31040363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43180-z
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