Mathematically Modeling the Involvement of Axons in Leber's Hereditary Optic Neuropathy

PURPOSE. Leber's hereditary optic neuropathy (LHON), a mitochondrial disease, has clinical manifestations that reflect the initial preferential involvement of the papillomacular bundle (PMB). The present study seeks to predict the order of axonal loss in LHON optic nerves using the Nerve Fiber...

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Autors principals: Pan, Billy X., Ross-Cisneros, Fred N., Carelli, Valerio, Rue, Kelly S., Salomao, Solange R., Moraes-Filho, Milton N., Moraes, Milton N., Berezovsky, Adriana, Belfort, Rubens, Sadun, Alfredo A.
Format: Artigo
Idioma:Inglês
Publicat: The Association for Research in Vision and Ophthalmology 2012
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495603/
https://ncbi.nlm.nih.gov/pubmed/23060142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10452
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