Exosomal transfer of miR-1238 contributes to temozolomide-resistance in glioblastoma

BACKGROUND: Although temozolomide (TMZ) resistance is a significant clinical problem in glioblastoma (GBM), its underlying molecular mechanisms are poorly understood. In this study, we identified the role of exosomal microRNAs (miRNAs) from TMZ-resistant cells as important mediators of chemoresistan...

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Dettagli Bibliografici
Pubblicato in:EBioMedicine
Autori principali: Yin, Jianxing, Zeng, Ailiang, Zhang, Zhuoran, Shi, Zhumei, Yan, Wei, You, Yongping
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019
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Research paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491393/
https://ncbi.nlm.nih.gov/pubmed/30917935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.03.016
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