Deletion of FOXO1 in Chondrocytes Rescues the Effect of Diabetes on Mechanical Strength in Fracture Healing

Diabetes increases the risk of fracture, impairs fracture healing and causes rapid loss of the fracture callus cartilage, which was linked to increased FOXO1 expression in chondrocytes. We recently demonstrated that deletion of FOXO1 in chondrocytes blocked the premature removal of cartilage associa...

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Détails bibliographiques
Publié dans:Bone
Auteurs principaux: Lu, Yongjian, Alharbi, Mohammed, Zhang, Citong, O’Connor, J. Patrick, Graves, Dana T.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491266/
https://ncbi.nlm.nih.gov/pubmed/30904630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2019.03.026
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