Deletion of FOXO1 in Chondrocytes Rescues the Effect of Diabetes on Mechanical Strength in Fracture Healing

Diabetes increases the risk of fracture, impairs fracture healing and causes rapid loss of the fracture callus cartilage, which was linked to increased FOXO1 expression in chondrocytes. We recently demonstrated that deletion of FOXO1 in chondrocytes blocked the premature removal of cartilage associa...

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Pubblicato in:Bone
Autori principali: Lu, Yongjian, Alharbi, Mohammed, Zhang, Citong, O’Connor, J. Patrick, Graves, Dana T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491266/
https://ncbi.nlm.nih.gov/pubmed/30904630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2019.03.026
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