TNF-α Mediates Diabetes-Enhanced Chondrocyte Apoptosis During Fracture Healing and Stimulates Chondrocyte Apoptosis Through FOXO1

To gain insight into the effect of diabetes on fracture healing, experiments were carried out focusing on chondrocyte apoptosis during the transition from cartilage to bone. Type 1 diabetes was induced in mice by multiple low-dose streptozotocin injections, and simple transverse fractures of the tib...

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Autors principals: Kayal, Rayyan A, Siqueira, Michelle, Alblowi, Jazia, McLean, Jody, Krothapalli, Nanarao, Faibish, Dan, Einhorn, Thomas A, Gerstenfeld, Louis C, Graves, Dana T
Format: Artigo
Idioma:Inglês
Publicat: Wiley Subscription Services, Inc., A Wiley Company 2010
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154002/
https://ncbi.nlm.nih.gov/pubmed/20200974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.59
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